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In particular, GSTP1-1 is able to protect the tumor cells from apoptosis signals by inhibiting c-Jun N-terminal kinase (JNK)a member of the MAPK pathwaynon-catalytically, by direct proteinprotein association 25,26

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It is understood that there will be no obvious damage in the brain area in the early stage of Ca 2+ imbalance, but a series of serious and persistent Ca 2+ -dependent cytotoxicity will occur later [12]